By Sheldon J. Park,Jennifer R. Cochran
Experimental protein engineering and computational protein layout are large yet complementary suggestions for constructing proteins with altered or novel structural homes and organic features. through describing state-of-the-art advances in either one of those fields, Protein Engineering and Design goals to domesticate a synergistic method of protein science.
Experimental Protein Engineering
The first half the ebook discusses experimental methods to protein engineering and starts off by way of describing a number of high-throughput screening structures for protein engineering. Key innovations used for range iteration also are mentioned. the following few chapters current examples of therapeutics, enzymes, biomaterials, and different proteins which have been engineered by way of rational or combinatorial ways. The part finishes with a bankruptcy at the use of non-natural amino acids in protein engineering.
Computational Protein Design
The moment half the ebook introduces computational protein layout, starting with a bankruptcy on computational and informatics algorithms utilized in protein engineering. center parts of computational protein layout are then mentioned intimately, and examples of heuristic protein layout are supplied. next chapters current examples of the way computational layout has performed a serious function in advancing the sector of protein engineering. Concluding with a bankruptcy outlining present demanding situations within the box, this ebook makes computational protein layout and diversity-oriented protein engineering broadly available to a large viewers in academia and alike.
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Extra info for Protein Engineering and Design
Protein Engineering and Design by Sheldon J. Park,Jennifer R. Cochran